Human Cytochrome P450 2E1, CYP2E1 ELISA Kit

SKU: E1274Hu

Size:96 Tests-1 Kit

Background:A cytochrome P450 monooxygenase involved in the metabolism of fatty acids (PubMed: 10553002, PubMed: 18577768). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase) (PubMed: 10553002, PubMed: 18577768). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids (PubMed: 10553002, PubMed: 18577768). May be involved in the oxidative metabolism of xenobiotics (Probable).

Research_area:Cardiovascular

Applications:ELISA

Target_protein:CYP2E1

Reactivity:Human

Assay type:Sandwich

Sensitivity:9.54ng/L

Detection range:20-6000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Cytochrome P450 2E1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P05181

MASS(Da):56,849

GeneID:1571

Synonyms:4-nitrophenol 2-hydroxylase;CYP2E1;CYPIIE1;Cytochrome P450 2E1;Cytochrome P450-J

Gene names:CYP2E1

Standard solution:6400ng/L