Human Collectin-12, COLEC12 ELISA Kit

SKU: E5083Hu

Size:96 Tests-1 Kit

Background:Scavenger receptor that displays several functions associated with host defense. Promotes binding and phagocytosis of Gram-positive, Gram-negative bacteria and yeast. Mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells. Binds to several carbohydrates including Gal-type ligands, D-galactose, L- and D-fucose, GalNAc, T and Tn antigens in a calcium-dependent manner and internalizes specifically GalNAc in nurse-like cells. Binds also to sialyl Lewis X or a trisaccharide and asialo-orosomucoid (ASOR). May also play a role in the clearance of amyloid-beta in Alzheimer disease.

Research_area:Immunology

Applications:ELISA

Target_protein:COLEC12

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.043ng/ml

Detection range:0.1-40ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Collectin-12

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q5KU26

MASS(Da):81,515

GeneID:81035

Synonyms:CL-P1;COLEC 12;COLEC12;Collectin placenta protein 1;Collectin-12;hCL-P1;Nurse cell scavenger receptor 2;Scavenger receptor class A member 4;Scavenger receptor with C-type lectin;

Gene names:COLEC12

Standard solution:48ng/ml