Human Coiled Coil and C2 Domain Containing Protein 1A, CC2D1A ELISA Kit

SKU: E4454Hu

Size:96 Tests-1 Kit

Background:Transcription factor that binds specifically to the DRE (dual repressor element) and represses HTR1A gene transcription in neuronal cells. The combination of calcium and ATP specifically inactivates the binding with FRE. May play a role in the altered regulation of HTR1A associated with anxiety and major depression. Mediates HDAC-independent repression of HTR1A promoter in neuronal cell. Performs essential function in controlling functional maturation of synapses (By similarity). Plays distinct roles depending on its localization. When cytoplasmic, acts as a scaffold protein in the PI3K/PDK1/AKT pathway. Repressor of HTR1A when nuclear. In the centrosome, regulates spindle pole localization of the cohesin subunit SCC1/RAD21, thereby mediating centriole cohesion during mitosis.

Research_area:Others

Applications:ELISA

Target_protein:CC2D1A

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.022ng/ml

Detection range:0.05-20ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Coiled Coil and C2 Domain Containing Protein 1A

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q6P1N0

MASS(Da):104,062

GeneID:54862

Synonyms:Akt kinase-interacting protein 1;CC2D1A;Coiled-coil and C2 domain-containing protein 1A;Five prime repressor element under dual repression-binding protein 1;FRE under dual repression-binding protein 1;Freud-1;Putative NF-kappa-B-activating protein 023N

Gene names:CC2D1A

Standard solution:24ng/ml