Human cluster Of differentiation 44,CD44 ELISA KIT

SKU: E0239Hu

Size:96 Tests-1 Kit

Background:Cell-surface receptor that plays a role in cell-cell interactions, cell adhesion and migration, helping them to sense and respond to changes in the tissue microenvironment (PubMed:16541107, PubMed:19703720, PubMed:22726066). Participates thereby in a wide variety of cellular functions including the activation, recirculation and homing of T-lymphocytes, hematopoiesis, inflammation and response to bacterial infection (PubMed:7528188). Engages, through its ectodomain, extracellular matrix components such as hyaluronan/HA, collagen, growth factors, cytokines or proteases and serves as a platform for signal transduction by assembling, via its cytoplasmic domain, protein complexes containing receptor kinases and membrane proteases (PubMed:18757307, PubMed:23589287). Such effectors include PKN2, the RhoGTPases RAC1 and RHOA, Rho-kinases and phospholipase C that coordinate signaling pathways promoting calcium mobilization and actin-mediated cytoskeleton reorganization essential for cell migration and adhesion (PubMed:15123640). {ECO:0000269|PubMed:15123640, ECO:0000269|PubMed:16541107, ECO:0000269|PubMed:18757307, ECO:0000269|PubMed:19703720, ECO:0000269|PubMed:22726066, ECO:0000269|PubMed:23589287, ECO:0000269|PubMed:7528188}.

Research_area:

Applications:ELISA

Target_protein:CD44

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.57ng/mL

Detection range:1-64ng/mL

Sample type:Serum, plasma or other biological fluids

Full product name:cluster Of differentiation 44

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P16070

MASS(Da):81538

GeneID:960

Synonyms:CD44 LHR MDU2 MDU3 MIC4

Gene names:CD44

Standard solution:128ng/mL