Human Cluster of Differentiation 22,CD22 ELISA KIT

SKU: E7170Hu

Size:96 Tests-1 Kit

Background:Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.

Research_area:

Applications:ELISA

Target_protein:CD22

Reactivity:Human

Assay type:Sandwich

Sensitivity:9.03mg/L

Detection range:20-4500mg/L

Sample type:Serum, plasma or other biological fluids

Full product name:Cluster of Differentiation 22

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P20273

MASS(Da):95348

GeneID:933

Synonyms:CD22 SIGLEC2

Gene names:CD22

Standard solution:4800mg/L