Human Claudin 10, CLDN10 ELISA Kit

SKU: E2308Hu

Size:96 Tests-1 Kit

Background:Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Involved in the regulation of paracellular epithelia permeability to ions in multiple organs. It acts as a paracellular ion channel probably forming permselective pores; isoform 1 appears to create pores preferentially permeable to cations and isoform 2 for anions. In sweat glands and in the thick ascending limb (TAL) of Henle's loop in kidney, it controls paracellular sodium permeability which is essential for proper sweat production and renal function (PubMed:19383724, PubMed:28771254, PubMed:28686597).

Research_area:Signal Transduction

Applications:ELISA

Target_protein:CLDN10

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.051ng/ml

Detection range:0.1-35ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Claudin 10

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P78369

MASS(Da):24,488

GeneID:9071

Synonyms:Claudin-10;CLDN10;CPETRL3;HELIX;Oligodendrocyte-specific protein-like;OSPL;OSP-L;OSP-like

Gene names:CLDN10

Standard solution:40ng/ml