Human Chloride Channel Accessory 1, CLCA1 ELISA Kit

SKU: E2891Hu

Size:96 Tests-1 Kit

Background:Chloride channel accessory 1 is a protein that in humans is encoded by the CLCA1 gene. This gene encodes a member of the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same region on chromosome 1p31-p22 and share a high degree of homology in size, sequence, and predicted structure, but differ significantly in their tissue distributions. The encoded protein is expressed as a precursor protein that is processed into two cell-surface-associated subunits, although the site at which the precursor is cleaved has not been precisely determined. The encoded protein may be involved in mediating calcium-activated chloride conductance in the intestine. Protein structure prediction methods suggest the N-terminal region of CLCA1 protein is a zinc metalloprotease.

Research_area:Signal Transduction

Applications:ELISA

Target_protein:CLCA1

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.095ng/ml

Detection range:0.2-60ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Chloride Channel Accessory 1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P35523

MASS(Da):108,626

GeneID:1180

Synonyms:Chloride Channel protein 1;Chloride Channel protein, skeletal muscle;CLC1;ClC-1;CLCA1

Gene names:CLCN1

Standard solution:80ng/ml