Human CD23/FCER2 ELISA Kit PicoKine®

SKU: EK0912

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: FCER2

Specificity: Natural and recombinant human CD23

Background: CD23, also known as Fc epsilon RII, or FcεRII, is the low-affinity receptor for IgE, an antibody isotype involved in allergy and resistance to parasites, and is important in regulation of IgE levels. There are two forms of CD23: CD23a and CD23b. CD23a is present on follicular B cells, whereas CD23b requires IL-4 to be expressed on T-cells, monocytes, Langerhans cells, eosinophils, and macrophages. As part of a mapping of multiple probes to specific bands on chromosome 19 by fluorescence in situ hybridization, the FCE2 gene was assigned to 19p13.3. CD23 (FCE2) is a key molecule for B-cell activation and growth. It is the low-affinity receptor for IgE. The truncated molecule can be secreted, then functioning as a potent mitogenic growth factor.

Immunogen: Expression system for standard: NS0; Immunogen sequence: D48-S321

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Reconstitution:

Reference:

Uniprot ID: P06734

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 2208

Protein Name: Low affinity immunoglobulin epsilon Fc receptor

Gene Full Name: Fc epsilon receptor II

Synonyms: BLAST 2; CD23; CD23A; CLEC4J; Fc epsilon RII; FCE2; FCER2; IGEBF; Lymphocyte IgE receptor