Human Caspase 9,CASP9 ELISA KIT

SKU: E4994Hu

Size:96 Tests-1 Kit

Background:Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP).; Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.

Research_area:

Applications:ELISA

Target_protein:CASP9

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.64ng/ml

Detection range:1.88-120ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P55211

MASS(Da):46281

GeneID:842

Synonyms:CASP9 MCH6

Gene names:CASP9

Standard solution:240ng/ml