Human/Canine/Porcine Insulin ELISA Kit PicoKine®

SKU: EK2287

Size: 96 wells/kit, with removable strips.

Storage: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human,Canine,Porcine

Applications: ELISA

Application Details:

Gene Name: INS

Specificity:

Background: Insulin is a peptide hormone produced by beta cells of the pancreatic islets encoded in humans by the insulin (INS) gene. This gene encodes insulin, a peptide hormone that plays a vital role in the regulation of carbohydrate and lipid metabolism. After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified, including insulin-dependent diabetes mellitus, permanent neonatal diabetes diabetes mellitus, maturity-onset diabetes of the young type 10 and hyperproinsulinemia. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region.

Immunogen: Expression system for standard: E.coli; Immunogen sequence: F25-N110

Clonality:

Contents:

Purification:

Reconstitution:

Reference:

Uniprot ID: P01308

Host:

Concentration:

Conjugate:

Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

Isotype:

Phospho_site:

Clone Number:

Observed Molecular Weight:

Calculated Molecular Weight:

Gene ID: 3630

Protein Name: Insulin [Cleaved into: Insulin B chain; Insulin A chain]

Gene Full Name: insulin

Synonyms: ILPR; INS; IRDN