Human Calreticulin 3, CALR3 ELISA Kit

SKU: E2950Hu

Size:96 Tests-1 Kit

Background:Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER (PubMed: 7876246). Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export (PubMed: 11149926). Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis (By similarity). Present in the cortical granules of non-activated oocytes, is exocytosed during the cortical reaction in response to oocyte activation and might participate in the block to polyspermy (By similarity).

Research_area:Tags & Cell Markers

Applications:ELISA

Target_protein:CALR

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.24ng/ml

Detection range:0.5-150ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Calreticulin 3

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P27797

MASS(Da):48,142

GeneID:811

Synonyms:CALR;Calregulin;Calreticulin;CRP55;Endoplasmic reticulum resident protein 60;ERp60;grp60;HACBP

Gene names:CALR

Standard solution:160ng/ml