Human C-type Lectin Domain Family 4 Member C, CLEC4C ELISA Kit

SKU: E5132Hu

Size:96 Tests-1 Kit

Background:Lectin-type cell surface receptor which may play a role in antigen capturing by dendritic cells (PubMed: 11748283, PubMed: 21880719, PubMed: 25995448). Specifically recognizes non-sialylated galactose-terminated biantennary glycans containing the trisaccharide epitope Gal(beta1-3/4)GlcNAc(beta1-2)Man (PubMed: 21880719, PubMed: 25995448). Binds to serum IgG (PubMed: 25995448). Efficiently targets ligand into antigen-processing and Peptide-loading compartments for presentation to T-cells (PubMed: 11748283). May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells (PubMed: 11748283, PubMed: 21880719). May act as a signaling receptor that activates protein-tyrosine kinases and mobilizes intracellular calcium (PubMed: 11748283).

Research_area:Others

Applications:ELISA

Target_protein:CLEC4C

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.054ng/ml

Detection range:0.1-40ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:C-Type Lectin Domain Family 4 Member C

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q8WTT0

MASS(Da):25,038

GeneID:170482

Synonyms:BDCA-2;Blood dendritic cell antigen 2;CD antigen CD303;CLEC4C;C-type lectin domain family 4 member C;C-type lectin superfamily member 7;Dendritic lectin

Gene names:CLEC4C

Standard solution:48ng/ml