Human Autophagy related protein 16-like 1,ATG16L1 ELISA KIT

SKU: E7368Hu

Size:96 Tests-1 Kit

Background:Plays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a membrane-bound activated form of LC3 named LC3-II. Thereby, controls the elongation of the nascent autophagosomal membrane (PubMed:24553140, PubMed:23376921, PubMed:24954904, PubMed:27273576, PubMed:23392225). Regulates mitochondrial antiviral signaling (MAVS)-dependent type I interferon (IFN-I) production (PubMed:25645662). Negatively regulates NOD1- and NOD2-driven inflammatory cytokine response (PubMed:24238340). Instead, promotes with NOD2 an autophagy-dependent antibacterial pathway (PubMed:20637199). Plays a role in regulating morphology and function of Paneth cell (PubMed:18849966). {ECO:0000269|PubMed:18849966, ECO:0000269|PubMed:22749352, ECO:0000269|PubMed:23376921, ECO:0000269|PubMed:23392225, ECO:0000269|PubMed:24238340, ECO:0000269|PubMed:24553140, ECO:0000269|PubMed:24954904, ECO:0000269|PubMed:25645662, ECO:0000269|PubMed:27273576}.

Research_area:

Applications:ELISA

Target_protein:ATG16L1

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.026ng/ml

Detection range:0.05-30ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Autophagy related protein 16-like 1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q676U5

MASS(Da):68265

GeneID:55054

Synonyms:ATG16L1 APG16L UNQ9393/PRO34307

Gene names:ATG16L1

Standard solution:32ng/ml