Human Atp Synthase Subunit Beta, Mitochondrial, ATP5B ELISA Kit

SKU: E3614Hu

Size:96 Tests-1 Kit

Background:Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core, and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Subunits alpha and beta form the catalytic core in F1. Rotation of the central stalk against the surrounding alpha3beta3 subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.

Research_area:Tags & Cell Markers

Applications:ELISA

Target_protein:ATP5B

Reactivity:Human

Assay type:Sandwich

Sensitivity:7.32ng/L

Detection range:15-3000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:ATP Synthase subunit beta, mitochondrial

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P06576

MASS(Da):56,560

GeneID:506

Synonyms:ATP Synthase F1 subunit beta;ATP Synthase subunit beta, mitochondrial;ATP5B;ATPMB;ATPSB;HEL-S-271

Gene names:ATP5F1B

Standard solution:3200ng/L