Human Aryl Hydrocarbon Receptor Repressor, AHRR ELISA Kit

SKU: E2832Hu

Size:96 Tests-1 Kit

Background:Mediates dioxin toxicity and is involved in regulation of cell growth and differentiation. Represses the transcription activity of AHR by competing with this transcription factor for heterodimer formation with the ARNT and subsequently binding to the xenobiotic response element (XRE) sequence present in the promoter regulatory region of variety of genes. Represses CYP1A1 by binding the XRE sequence and recruiting ANKRA2, HDAC4 and/or HDAC5. Autoregulates its expression by associating with its own XRE site.

Research_area:Others

Applications:ELISA

Target_protein:AHRR

Reactivity:Human

Assay type:Sandwich

Sensitivity:5.35ng/L

Detection range:10-2000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Aryl Hydrocarbon Receptor Repressor

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:A9YTQ3

MASS(Da):76,265

GeneID:57491

Synonyms:AhR repressor;AHRR;Aryl hydrocarbon receptor repressor;bHLHe77;Class E basic helix-loop-helix protein 77

Gene names:AHRR

Standard solution:2400ng/L