Human Alpha-Actinin-4, ACTN-4 ELISA Kit

SKU: E4927Hu

Size:96 Tests-1 Kit

Background:F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein (Probable). Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation (PubMed: 15772161). Involved in tight junction assembly in epithelial cells probably through interaction with MICALL2. Links MICALL2 to the actin cytoskeleton and recruits it to the tight junctions (By similarity). May also function as a transcriptional coactivator, stimulating transcription mediated by the nuclear hormone receptors PPARG and RARA (PubMed: 22351778).

Research_area:Signal Transduction

Applications:ELISA

Target_protein:ACTN4

Reactivity:Human

Assay type:Sandwich

Sensitivity:9.49ng/L

Detection range:20-4500ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Alpha-Actinin-4

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:O43707

MASS(Da):104,854

GeneID:81

Synonyms:ACTN 4;ACTN4;Alpha-actinin-4;Non-muscle alpha-actinin 4

Gene names:ACTN4

Standard solution:4800ng/L