Human Aggrecan/ACAN ELISA Kit PicoKine®

SKU: EK0909

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: ACAN

Specificity: Natural and recombinant human Aggrecan

Background: Aggrecan, also known as cartilage-specific proteoglycan core protein (CSPCP) or chondroitin sulfate proteoglycan 1, is a protein that in humans is encoded by the ACAN gene. It is a critical component for cartilage structure and the function of joints. Aggrecan provides intervertebral disc and cartilage with the ability to resist compressive loads. The localized high concentrations of aggrecan provide the osmotic properties necessary for normal tissue function with the GAGs producing the swelling pressure that counters compressive loads on the tissue. This functional ability is dependent on a high GAG/aggrecan concentration being present in the tissue extracellular matrix. Also, Aggrecan plays an important role in the organization of the extracellular spaces between neurons in the brain.

Immunogen: Expression system for standard: NS0; Immunogen sequence: V20-R675

Clonality:

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Reconstitution:

Reference:

Uniprot ID: P16112

Host:

Concentration:

Conjugate:

Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

Isotype:

Phospho_site:

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Observed Molecular Weight:

Calculated Molecular Weight:

Gene ID: 176

Protein Name: Aggrecan core protein

Gene Full Name: aggrecan

Synonyms: ACAN; AGC1; AGCAN; aggrecan; CSPG1; CSPGCP; MSK16; SEDK