Human 6-phosphofructo-2-kinase, Fructose-2, 6-biphosphatase 2, PFKFB2 ELISA Kit

SKU: E3191Hu

Size:96 Tests-1 Kit

Background:6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 is an enzyme that in humans is encoded by the PFKFB2 gene. The protein encoded by this gene is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. This protein regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. Two transcript variants encoding two different isoforms have been found for this gene.

Research_area:Others

Applications:ELISA

Target_protein:PFKFB2

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.017ng/ml

Detection range:0.05-15ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:O60825

MASS(Da):58,477

GeneID:5208

Synonyms:6PF-2-K/Fru-2,6-P2ase 2;6PF-2-K/Fru-2,6-P2ase heart-type isozyme [Includes: 6-phosphofructo-2-kinase;6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2;Fructose-2,6-bisphosphatase;PFK/FBPase 2;PFK-2/FBPase-2;PFKFB2

Gene names:PFKFB2

Standard solution:16ng/ml