HSD3B7 Antibody - Cat. #: CSB-PA861999LA01HU

SKU: CSB-PA861999LA01HU

Size :50ug

Clone Number:

Aliases:HSD3B73 beta-hydroxysteroid dehydrogenase type 7 antibody; 3 beta-hydroxysteroid dehydrogenase type VII antibody; 3-beta-HSD VII antibody; 3-beta-hydroxy-Delta(5)-C27 steroid oxidoreductase antibody; C(27) 3-beta-HSD antibody; EC 1.1.1.- antibody; Cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase antibody; EC 1.1.1.181 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9H2F3

Immunogen:Recombinant Human 3 beta-hydroxysteroid dehydrogenase type 7 protein (131-197AA)

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB, IF; Recommended dilution: WB:1:500-1:5000, IF:1:50-1:200

Background:The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. HSD VII is active against four 7-alpha-hydroxylated sterols. Does not metabolize several different C(19/21) steroids as substrates. Involved in bile acid synthesis (PubMed:11067870). Plays a key role in cell positioning and movement in lymphoid tissues by mediating degradation of 7-alpha,25-dihydroxycholesterol (7-alpha,25-OHC): 7-alpha,25-OHC acts as a ligand for the G protein-coupled receptor GPR183/EBI2, a chemotactic receptor for a number of lymphoid cells.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Non-conjugated

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:HSD3B7

Research Areas:Signal transduction