HOMER2 antibody , Cat. # FNab03964

SKU: FNab03964

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. May also couple GRM1 to PI3 kinase through its interaction with AGAP2. Isoforms can be differently regulated and may play an important role in maintaining the plasticity at glutamatergic synapses(PubMed:9808459). Required for normal hearing(PubMed:25816005).

Immunogen:homer homolog 2(Drosophila)

Synonyms:

Observed MW:39 kDa

Uniprot ID:Q9NSB8

Reactivity:Human

Tested Application:ELISA, WB

Recommended dilution:WB: 1:500-1:2000

Gene ID:9455

Research Area:Neuroscience, Signal Transduction