HLA-G Polyclonal Antibody

SKU: E-AB-18031

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: HLA-G

Target Synonym: B2 microglobulin;DADB-15K14.8;HLA 6.0;HLA class I histocompatibility antigen alpha chain G;HLA class I histocompatibility antigen;alpha chain G;HLA class I molecule;HLA G;HLA G antigen;HLA G histocompatibility antigen class I G;HLA G3;HLA-G;HLA-G histocompatibility antigen;class I;HLA60;HLAG;HLAG;Major histocompatibility complex class I G;MHC class I antigen;MHC class I antigen G;MHC G;T-cell A locus;TCA

Research Areas: Cancer;Immunology

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human

Application: IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P17693

Accession:

Background: Human major histocompatibility complex (MHC) antigens,also referred to as human leukocyte antigens (HLA),are encoded by genes located on the short arm of chromosome 6 (6p21.3). HLA-G is a non-classical MHC class I molecule with multiple immunoregulatory properties. HLA-G exhibits a restricted pattern of expression that includes placental extravillous trophoblasts at the maternal-fetal interface,where it abolishes maternal immune cell activity against fetus and establishes immune tolerance. Aberrant expression of HLA-G has been found in a variety of human neoplastic diseases. It plays an important role in the escape of tumor cells from immunosurveillance.

Concentration: 1.26 mg/mL

Immunogen: Synthetic peptide of human HLA-G

Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method: Antigen affinity purification

Dilution: IHC 1:50-1:300

Calculated MW:

ObservedMW: