HLA-DPA1 Polyclonal Antibody

SKU: E-AB-18082

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: HLA-DPA1

Target Synonym: DP(W3);DP(W4);HLA class II histocompatibility antigen DP alpha 1 chain;HLA class II histocompatibility antigen DP alpha chain ;HLA DP1A;HLA DPA 1;HLA SB alpha chain;HLADP;HLADPA1 ;HLASB;HLASB histocompatibility type;Human MHC class II HLA SB alpha gene;Major histocompatibility complex class II DP alpha 1;MHC class II antigen;MHC class II DP3 alpha;MHC class II DPA1;MHC class II HLA DPA1 antigen;PLT1;Primed lymphocyte test 1

Research Areas: Cancer;Immunology

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human

Application: WB;IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P20036

Accession:

Background: HLA-DPA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta (DPB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules.

Concentration: 0.96 mg/mL

Immunogen: Synthetic peptide of human HLA-DPA1

Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method: Antigen affinity purification

Dilution: WB 1:500-1:2000;IHC 1:40-1:200

Calculated MW: 29 kDa

ObservedMW: Refer to figures