H2AFX Monoclonal Antibody

SKU: BT-MCA3284

Size:100μL

Background:Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.

Research_area:Epigenetics and Nuclear Signaling

Target_protein:H2AFX

applications:WB, IHC, ICC, FCM

Reactivity:Human

Clonality:Monoclonal

Clone ID:4A2D5

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:H2AFX

Immunogen:Purified recombinant fragment of human H2AFX expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):15.1kDa

UniProt accession:P16104

Synonyms:H2AX, H2A.X, H2A/X

GeneID:3014