GZMB Monoclonal Antibody

SKU: BT-MCA2658

Size:100μL

Background:This gene encodes a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing. Expression of this gene may be elevated in human patients with cardiac fibrosis. [provided by RefSeq, Sep 2016]

Research_area:Others

Target_protein:GZMB

applications:IHC

Reactivity:

Clonality:Monoclonal

Clone ID:2G12G7

Host:Mouse

Isotype:Mouse IgG2a

Gene Symbol/ Name:GZMB

Immunogen:Purified recombinant fragment of human GZMB (AA: 21-247) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):28kDa

UniProt accession:P10144

Synonyms:C11, HLP, CCPI, CGL1, CSPB, SECT, CGL-1, CSP-B, CTLA1, CTSGL1

GeneID:3002