GZMB antibody , Cat. # FNab03737

SKU: FNab03737

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases(aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3,-7,-9 and 10 to give rise to active enzymes mediating apoptosis.

Immunogen:granzyme B

Synonyms:CCPI, CGL 1, CGL1, CSP B, CSPB, CTLA1, CTSGL1, Endogenous granzyme B, Granzyme B, GZMB, HLP, SECT

Observed MW:33 kDa

Uniprot ID:P10144

Reactivity:Human

Tested Application:ELISA, WB, IHC, IF

Recommended dilution:WB: 1:500-1:2000; IHC: 1:50-1:500; IF: 1:50-1:500

Gene ID:3002

Research Area:Cancer, Immunology, Metabolism