GSDMD antibody , Cat. # FNab03670

SKU: FNab03670

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:GSDMD is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. GSDMD has been suggested to act as a tumor suppressor. Recently, GSDMD is identified as a new component of inflammasomes, and it is an executor of pyroptosis and required for interleukin-1? secretion. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.

Immunogen:gasdermin D

Synonyms:DF5L, DFNA5L, FKSG10, FLJ12150, gasdermin D, GSDMD, GSDMDC1

Observed MW:50-53 kDa

Uniprot ID:P57764

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, WB, IHC, IF

Recommended dilution:WB: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:10-1:100

Gene ID:79792

Research Area:Developmental biology