Granzyme M rabbit pAb

SKU: ES8807

Size: 100μL

Source:Rabbit

Applications:IHC;IF;ELISA

Reactivity:Human;Rat;Mouse;

Dilution:IHC-p 1:50-200, ELISA 1:10000-20000

Immunogen:Synthetic peptide from human protein at AA range: 207-256

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):

Human_gene_id:3004

Human_swiss_prot_no:P51124

Subcellular_location:Secreted. Cytoplasmic granule. Granules of large granular lymphocytes.

Other_name:Granzyme M (EC 3.4.21.-;Met-1 serine protease;Hu-Met-1;Met-ase;Natural killer cell granular protease)

Background:Human natural killer (NK) cells and activated lymphocytes express and store a distinct subset of neutral serine proteases together with proteoglycans and other immune effector molecules in large cytoplasmic granules. These serine proteases are collectively termed granzymes and include 4 distinct gene products: granzyme A, granzyme B, granzyme H, and the protein encoded by this gene, granzyme M. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012],