GeneBio Systems
GPC3 Polyclonal Antibody
GPC3 Polyclonal Antibody
SKU:E-AB-53438
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Size::120μL
Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
Exp date:12 months
Category ID_II:Primary Antibodies
Category ID_III:Polyclonal Antibodies
Abbreviation:GPC3
Target Synonym:DGSX;Glypican proteoglycan 3;Glypican-3 [Precursor];Gpc3;GPC3;GTR2 2;GTR2-2;Heparan sulphate proteoglycan;Intestinal protein OCI 5;Intestinal protein OCI-5;MXR7;OCI 5;OCI-5;OCI5;SDYS;Secreted glypican-3;SGB;SGBS;SGBS1
Research Areas:Cancer;Developmental Biology;Signal Transduction;Stem Cells
Conjugation:Unconjugated
Host:Rabbit
Species reactivity:Human;Mouse
Application:IHC
Isotype:IgG
Clonality:Polyclonal
Clone NO.:
UNIProt ID:P51654
Accession:
Background:Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants.
Concentration:1.8 mg/mL
Immunogen:Synthetic peptide of human GPC3
Buffer:PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Purification method:Antigen affinity purification
Dilution:IHC 1:40-1:200
Calculated MW:
ObservedMW:
