Glucosidase IIα rabbit pAb

SKU: ES5316

Size: 100μL

Source:Rabbit

Applications:WB;IHC;IF;ELISA

Reactivity:Human;Mouse

Dilution:Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.

Immunogen:The antiserum was produced against synthesized peptide derived from human GANAB. AA range:242-291

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):107kD

Human_gene_id:23193

Human_swiss_prot_no:Q14697

Subcellular_location:Endoplasmic reticulum . Golgi apparatus . Melanosome . Identified by mass spectrometry in melanosome fractions from stage I to stage IV. .

Other_name:GANAB; G2AN; KIAA0088; Neutral alpha-glucosidase AB; Alpha-glucosidase 2; Glucosidase II subunit alpha

Background:This gene encodes the alpha subunit of glucosidase II and a member of the glycosyl hydrolase 31 family of proteins. The heterodimeric enzyme glucosidase II plays a role in protein folding and quality control by cleaving glucose residues from immature glycoproteins in the endoplasmic reticulum. Expression of the encoded protein is elevated in lung tumor tissue and in response to UV irradiation. Mutations in this gene cause autosomal-dominant polycystic kidney and liver disease. [provided by RefSeq, Jul 2016],