GH Polyclonal Antibody

SKU: BT-AP09485

Size:100μL

Background:The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature.

Research_area:Developmental biology; Signal transduction; Epigenetics and nuclear signaling; Cancer; Neuroscience

Target_protein:GH1

applications:IHC-p, IF, ELISA

Reactivity:Human, Rat, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Somatotropin

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):

UniProt accession:Human: P01241/P01242

Synonyms:Somatotropin ;Growth hormone;GH;GH-N;Growth hormone 1;Pituitary growth hormone; Somatotropin; Growth hormone; GH; GH-N; Growth hormone 1; Pituitary growth hormone Growth hormone variant; GH-V; Growth hormone 2; Placenta-specific growth hormone

GeneID:Human: 2688