GCKR Polyclonal Antibody

SKU: BT-AP03507

Size:100μL

Background:GCKR encodes glucokinase regulator belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. GCKR is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY).

Research_area:Signal Transduction; Metabolism

Target_protein:GCKR

applications:WB, ELISA

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:GCKR Antibody

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):68685

UniProt accession:Human: Q14397; Mouse: Q91X44; Rat: Q07071

Synonyms:GCKR; Glucokinase regulatory protein; Glucokinase regulator

GeneID:Human: 2646; Mouse: 231103; Rat: 25658