GADD34 rabbit pAb

SKU: ES8613

Size: 100μL

Source:Rabbit

Applications:WB;ELISA

Reactivity:Human;Rat;Mouse;

Dilution:WB 1:500-2000, ELISA 1:10000-20000

Immunogen:Synthetic peptide from human protein at AA range: 430-490

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):73kD

Human_gene_id:23645

Human_swiss_prot_no:O75807

Subcellular_location:Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side . Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side . Associates with membranes via an N-terminal amphipathic intramembrane region. .

Other_name:Protein phosphatase 1 regulatory subunit 15A (Growth arrest and DNA damage-inducible protein GADD34) (Myeloid differentiation primary response protein MyD116 homolog)

Background:This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The induction of this gene by ionizing radiation occurs in certain cell lines regardless of p53 status, and its protein response is correlated with apoptosis following ionizing radiation. [provided by RefSeq, Jul 2008],