G3BP1 (Ab-232) Antibody - Cat. #: CSB-PA057449

SKU: CSB-PA057449

Size :100ul

Clone Number:

Aliases:ATP dependent DNA helicase VIII antibody; ATP-dependent DNA helicase VIII antibody; G3BP antibody; G3BP stress granule assembly factor 1 antibody; G3BP-1 antibody; G3bp1 antibody; G3BP1_HUMAN antibody; GAP binding protein antibody; GAP SH3 domain binding protein 1 antibody; GAP SH3 domain-binding protein 1 antibody; GTPase activating protein (SH3 domain) binding protein 1 antibody; hDH VIII antibody; Human DNA helicase VIII antibody; MGC111040 antibody; Ras GTPase activating protein binding protein 1 antibody; Ras GTPase activating protein SH3 domain binding protein antibody; Ras GTPase-activating protein-binding protein 1 antibody; RasGAP associated endoribonuclease G3BP antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q13283

Immunogen:Peptide sequence around aa.230~234 (S-S-S-P-A) derived from Human G3BP-1.

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB, IHC; WB:1:500-1:1000, IHC:1:50-1:200

Background:May be a regulated effector of stress granule assembly. Phosphorylation-dependent sequence-specific endoribonuclease in vitro. Cleaves exclusively between cytosine and adenine and cleaves MYC mRNA preferentially at the 3'-UTR. ATP- and magnesium-dependent helicase. Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3' tail or hanging tails at both 5'- and 3'-ends. Unwinds DNA/DNA, RNA/DNA, and RNA/RNA substrates with comparable efficiency. Acts unidirectionally by moving in the 5' to 3' direction along the bound single-stranded DNA.

Tao WA, et al. (2005) Nat Methods. 2 (8): 591-598.
Zheng H, et al. (2005) Mol Cell Proteomics. 4(6):721-730.
Beausoleil SA, et al. (2004) Proc Natl Acad Sci USA.101 (33): 12130-12135.
Tourrihre H, et al. (2003) J Cell Biol.160 (6): 823-831.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Conjugate:Non-conjugated

Buffer:Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:G3BP1

Research Areas:Epigenetics and Nuclear Signaling