FXN antibody , Cat. # FNab03255

SKU: FNab03255

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:FXN, also named as FRDA, X25, m81-FXN, d-FXN, m78-FXN and i-FXN, belongs to the frataxin family. It promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe2+ to proteins involved in these pathways. FXN may play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe2+ to Fe3+; the oligomeric form but not the monomeric form has in vitro ferroxidase activity. FXN is cleaved to be 4 chains. The mature form of FXN is 14 or 18kDa.

Immunogen:frataxin

Synonyms:CyaY, d FXN, FA, FARR, frataxin, Frataxin(81 210), Frataxin, mitochondrial, FRDA, Friedreich ataxia protein, FXN, i FXN Frataxin(56 210), m56 FXN Frataxin(78 210), m78 FXN Frataxin mature form, m81 FXN, X25

Observed MW:14 kDa

Uniprot ID:Q16595

Reactivity:Human

Tested Application:ELISA, WB

Recommended dilution:WB: 1:500-1:2000

Gene ID:2395

Research Area:Cancer, Neuroscience, Metabolism, Signal Transduction