Fluor® Violet 450 Anti-Mouse CD122 Antibody[TM-Beta 1]

SKU: AN00418Q

Size:100Tests

Storage:This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Flow Cytometry Antibodies

Abbreviation:CD122

Target Synonym:IL-2 Receptor β chain;IL-2Rβ

Research Areas:

Conjugation:Elab Fluor®Violet 450

Host:Rat

Species reactivity:Mouse

Application:FCM

Usage:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Isotype:Rat IgG2b, κ

Clonality:Monoclonal

Clone NO.:TM-Beta 1

UNIProt ID:P16297

Background:CD122 is a 70-75 kD IL-2 receptor β chain also known as IL-2Rβ, which is also shared by the IL-15 receptor. It is constitutively expressed by NK cells and at lower levels by T cells, B cells, monocytes, and macrophages. The IL-2Rβ chain can combine with either the common γ subunit (γc, CD132) alone or with the γc subunit and the IL-2Rα subunit (CD25) to generate intermediate or high affinity IL-2 receptor complexes, respectively. CD122 expression levels can be upregulated by activation. The TM-β1 antibody does inhibit IL-2 binding to the IL-2 receptor. CD122 is expressed on murine, but not human, CD8+ Tregs involved in the maintenance of T cell homeostasis.

Concentration:5 μL/Test

Control catalog number:E-AB-F09842Q

Immunogen:

Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant

Purification method:

Dilution:

GeneID:16185