FKBP5 Polyclonal Antibody

SKU: BT-AP15605

Size:100μL

Background:The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.

Research_area:Immunology; Signal transduction

Target_protein:FKBP5

applications:WB, ELISA

Reactivity:Human, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Peptidyl-prolyl cis-trans isomerase FKBP5

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):

UniProt accession:Human: Q13451; Mouse: Q64378

Synonyms:Peptidyl-prolyl cis-trans isomerase FKBP5 ;PPIase FKBP5;EC 5.2.1.8;51 kDa FK506-binding protein;51 kDa FKBP;FKBP-51;54 kDa progesterone receptor-associated immunophilin;Androgen-regulated

GeneID:Human: 2289