FKBP4 Polyclonal Antibody

SKU: E-AB-19050

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: FKBP4

Target Synonym: 51 kDa FK506-binding protein;52 kDa FK506 binding protein;52 kDa FK506-binding protein;52 kDa FKBP;59 kDa immunophilin;FK506 binding protein 4;FK506-binding protein 4;FKBP 4;FKBP 52;FKBP 59;FKBP-4;FKBP-52;FKBP4;FKBP4;FKBP51;FKBP52 protein;FKBP59;HBI;Hsp 56;HSP binding immunophilin;HSP-binding immunophilin;Hsp56;Immunophilin FKBP52;N-terminally processed;p52;p59;p59 protein;Peptidyl prolyl cis trans isomerase;Peptidyl-prolyl cis-trans isomerase FKBP4;Peptidylprolyl cis trans isomerase;PPIase;PPIase FKBP4;Rotamase;T cell FK506 binding protein 59kD

Research Areas: Cancer;Epigenetics and Nuclear Signaling;Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat

Application: WB;IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: Q02790

Accession:

Background: FKBP52 (FK506 binding protein 4) is a member of the immunophilin protein family that comprises intracellular protein effectors of immunosuppressive drugs,and it is known as a steroid receptor-associated protein. As a novel regulator of microtubule dynamics,FKBP52 is associated with the motor protein dynein and with the cytoskeleton during mitosis. FKBP52 is highly expressed in CNS regions susceptible to Alzheimer's,and plays a role in modulating toxicity of Abeta peptides. The protein can associate with the Tau function,and may help to decipher and modulate the events involved in Tau-induced neurodegeneration. In addition,FKBP52 is likely to play a role in growth and development of the male genitalia.

Concentration: 1.14 mg/mL

Immunogen: Fusion protein of human FKBP4

Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method: Antigen affinity purification

Dilution: WB 1:1000-1:5000;IHC 1:50-1:300

Calculated MW: 52 kDa

ObservedMW: Refer to figures