FKBP1A Polyclonal Antibody

SKU: E-AB-52794

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:FKBP1A

Target Synonym:12 kDa FK506-binding protein;12 kDa FKBP;Calstabin 1;FK506 binding protein 1;FK506 binding protein 12;FK506 binding protein 1A (12kD);FK506 binding protein 1A 12kDa;FK506 binding protein 1A;FK506 binding protein T cell 12 kD;FK506 binding protein;T cell;12 kD;FK506 binding protein12;FK506-binding protein 1A;FKB1A;FKBP 12;FKBP 1A;FKBP-12;FKBP-1A;FKBP1;FKBP12;FKBP12 Exip3;FKBP12C;fkbp1a;Immunophilin FKBP12;Peptidyl prolyl cis trans isomerase;Peptidyl-prolyl cis-trans isomerase FKBP1A;PKC12;PKCI2;PPIase;PPIase FKBP1A;Protein kinase C inhibitor 2;Rotamase

Research Areas:Cancer;Immunology

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:P62942

Accession:

Background:The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium. Multiple alternatively spliced variants, encoding the same protein, have been identified. The human genome contains five pseudogenes related to this gene, at least one of which is transcribed.

Concentration:0.96 mg/mL

Immunogen:Fusion protein of human FKBP1A

Buffer:PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method:Antigen affinity purification

Dilution:IHC 1:50-1:300

Calculated MW:

ObservedMW: