FITC Anti-Human CD86 Antibody[IT2.2]

SKU: GBS-F1269C

Size:100Tests

Storage:This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Flow Cytometry Antibodies

Abbreviation:CD86

Target Synonym:Activation B7-2 antigen;B7-2;B7.2;B70;BU63;CD28LG;CD28LG2;CD86;CTLA-4 Counter-Receptor B;CTLA-4 Counter-Receptor B7.2;ETC;ETC-1;Early T-cell costimulatory molecule;Early T-cell costimulatory molecule 1;FUN;FUN-1;LAB;LAB72;T-lymphocyte activation antigen C

Research Areas:Cell Biology;Costimulatory Molecules;Immunology;Neuroscience;Neuroscience Cell Markers

Conjugation:FITC

Host:Mouse

Species reactivity:Human

Application:FCM

Usage:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Isotype:Mouse IgG2b, κ

Clonality:Monoclonal

Clone NO.:IT2.2

UNIProt ID:P42081

Background:CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, monocytes/macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is the ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce costimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can bind to CD152 as well, also known as CTLA-4, to deliver an inhibitory signal to T cells.

Concentration:5 μL/Test

Control catalog number:E-AB-F09812C

Immunogen:

Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Purification method:

Dilution:

GeneID:942