FGF2 Monoclonal Antibody

SKU: BT-MCA3395

Size:100μL

Background:FGF2 is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. FGF2 is a single-chain polypeptide growth factor that plays a significant role in the process of wound healing and is a potent inducer of anguogenesis. Due to its basic pH, the factor is named FGF-2 (basic FGF, bFGF).Several different forms of the human protein exist ranging from 18-24 kDa in size due to the use of alternative start sites within the fgf-2 gene. It has a 55 percent amino acid residue identity to FIBROBLAST GROWTH FACTOR 1 and has potent heparin-binding activity. The growth factor is an extremely potent inducer of DNA synthesis in a variety of cell types from mesoderm and neuroectoderm lineages. It was originally named basic fibroblast growth factor based upon its chemical properties and to distinguish it from acidic fibroblast growth factor (FIBROBLAST GROWTH FACTOR 1).

Research_area:Cardiovascular

Target_protein:FGF2

applications:IHC

Reactivity:Human

Clonality:Monoclonal

Clone ID:2H5G2C11

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:FGF2

Immunogen:Purified recombinant fragment of FGF2 expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):

UniProt accession:P09038

Synonyms:BFGF, FGFB, HBGF-2, FGF2

GeneID:2247