FGB Monoclonal Antibody

SKU: BT-MCA3723

Size:100μL

Background:Fibrinogen beta chain, also known as FGB, is a gene found in humans and most other vertebrates with a similar system of blood coagulation.It is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency.

Research_area:Cardiovascular

Target_protein:FGB

applications:WB

Reactivity:Human

Clonality:Monoclonal

Clone ID:1F9

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:FGB

Immunogen:Purified recombinant fragment of human FGB (aa30-300) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):52kDa

UniProt accession:P02675

Synonyms:fibrinogen beta chain

GeneID:2244