FBXW2 Rabbit Polyclonal Antibody

SKU: BT-AP10012

Size:100μL

Background:F-box proteins are an expanding family of eukaryotic proteins characterized by an approximately 40 amino acid motif| the F box. Some F-box proteins have been shown to be critical for the ubiquitin-mediated degradation of cellular regulatory proteins. In fact| F-box proteins are one of the four subunits of ubiquitin protein ligases| called SCFs. SCF ligases bring ubiquitin conjugating enzymes to substrates that are specifically recruited by the different F-box proteins. Mammalian F-box proteins are classified into three groups based on the presence of either WD-40 repeats| leucine-rich repeats| or the presence or absence of other protein-protein interacting domains. This gene encodes the second identified member of the F-box gene family and contains multiple WD-40 repeats.

Research_area:Cell biology

Target_protein:FBXW2

applications:WB

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:FBXW2

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):49940

UniProt accession:Human: Q9UKT8; Mouse: Q60584; Rat: B2RZ17

Synonyms:FBXW2

GeneID:Human: 26190; Rat: 311881