FBXO7 Antibody - Cat. #: CSB-PA667562ESR2HU

SKU: CSB-PA667562ESR2HU

Size :50ul

Clone Number:

Aliases:F box only protein 7 antibody; F box protein 7 antibody; F-box only protein 7 antibody; FBX antibody; FBX07 antibody; FBX7 antibody; FBX7_HUMAN antibody; Fbxo7 antibody; PARK15 antibody; PKPS antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9Y3I1

Immunogen:Recombinant Human F-box only protein 7 protein (353-522AA)

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200

Background:Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes BIRC2 and DLGAP5. Plays a role downstream of PINK1 in the clearance of damaged mitochondria via selective autophagy (mitophagy) by targeting PARK2 to dysfunctional depolarized mitochondria. Promotes MFN1 ubiquitination.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:FBXO7

Research Areas:Epigenetics and Nuclear Signaling; Cell biology