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Gene Bio Systems

FBXO32 Antibody - Cat. #: CSB-PA996906

FBXO32 Antibody - Cat. #: CSB-PA996906

SKU:CSB-PA996906

Regular price €331,95 EUR
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Size :50ul

Clone Number:

Aliases:4833442G10Rik antibody; AI430017 antibody; Atrogin 1 antibody; Atrogin-1 antibody; ATROGIN1 antibody; Atrophy gene 1 antibody; F box only protein 32 antibody; F-box only protein 32 antibody; F-box protein 32 antibody; FBX32_HUMAN antibody; fbxo25 antibody; FBXO32 antibody; FLJ32424 antibody; MAFbx antibody; MGC108443 antibody; MGC137646 antibody; MGC33610 antibody; Muscle atrophy F box antibody; Muscle atrophy F box protein antibody; Muscle atrophy F-box protein antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q969P5

Immunogen:Fusion protein of Human FBXO32

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB, IHC; ELISA:1:1000-1:5000, WB:1:200-1:1000, IHC:1:25-1:100

Background:This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:FBXO32

Research Areas:Cardiovascular?Cell biology;Stem cells

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