FBL Antibody - Cat. #: CSB-PA919400

SKU: CSB-PA919400

Size :100ul

Clone Number:

Aliases:34 kD nucleolar scleroderma antigen antibody; 34 kDa nucleolar scleroderma antigen antibody; Fbl antibody; FBRL_HUMAN antibody; FIB antibody; FIB1 antibody; FLRN antibody; Histone-glutamine methyltransferase antibody; Nop1p antibody; RNA U3 small nucleolar interacting protein 1 antibody; RNU3IP1 antibody; rRNA 2' O methyltransferase fibrillarin antibody; rRNA 2'-O-methyltransferase fibrillarin antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P22087

Immunogen:Peptide sequence around aa.297~301( L-T-L-E-P) derived from Human Fibrillarin

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB; WB:1:500-1:1000

Background:Involved in pre-rRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.

Lischwe M.A., Ochs R.L., Reddy R., Cook R.G., Yeoman L.C., Tan E.M., Reichlin M., Busch H. J. Biol. Chem. 260:14304-14310(1985)
Yanagida M., Hayano T., Yamauchi Y., Shinkawa T., Natsume T., Isobe T., Takahashi N.J. Biol. Chem. 279:1607-1614(2004)
Wang Y., Liu J., Zhao H., Lue W., Zhao J., Yang L., Li N., Du X., Ke Y.Biochim. Biophys. Acta 1773:863-868(2007)

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Conjugate:Non-conjugated

Buffer:Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:FBL

Research Areas:Epigenetics and Nuclear Signaling;Tags & Cell Markers