FAP Antibody - Cat. #: CSB-PA101830

SKU: CSB-PA101830

Size :100ul

Clone Number:

Aliases:170 kDa melanoma membrane bound gelatinase antibody; 170 kDa melanoma membrane-bound gelatinase antibody; DPPIV antibody; FAP antibody; FAPA antibody; Fibroblast activation protein alpha antibody; Integral membrane serine protease antibody; SEPR_HUMAN antibody; Seprase antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q12884

Immunogen:Synthesized peptide derived from Human FAP-1.

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB, IHC; WB:1:500-1:3000, IHC:1:50-1:100

Background:In association with DPP4 is involved in the pericellular proteolysis of the extracellular matrix (ECM), the migration and invasion of endothelial cells into the ECM. May have a role in tissue remodeling during development and wound healing, and may contribute to invasiveness in malignant cancers.

Hendrik Ungefroren, J. Cell Sci., Aug 2001; 114: 2735.
Vladimir N. Ivanov, Mol. Cell. Biol., May 2003; 23: 3623 - 3635.
Vladimir N. Ivanov, J. Biol. Chem., Jan 2006; 281: 1840 - 1852.
T Sato, ience, Apr 1995; 268: 411 - 415.

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:FAP

Research Areas:Cancer;Cell biology;Signal transduction