FANCI Antibody - Cat. #: CSB-PA889120LA01HU

SKU: CSB-PA889120LA01HU

Size :50ug

Clone Number:

Aliases:FANCI antibody; FANCI gene antibody; FANCI_HUMAN antibody; Fanconi anemia group I protein antibody; Fanconi anemia; complementation group I antibody; FLJ10719 antibody; FLJ14658 antibody; KIAA1794 antibody; Protein FACI antibody; Protein FANCI antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9NVI1

Immunogen:Recombinant Human Fanconi anemia group I protein (180-252AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IF; Recommended dilution: IF:1:50-1:200

Background:Plays an essential role in the repair of DNA double-strand breaks by homologous recombination and in the repair of interstrand DNA cross-links (ICLs) by promoting FANCD2 monoubiquitination by FANCL and participating in recruitment to DNA repair sites. Required for maintenance of chromosomal stability. Specifically binds branched DNA: binds both single-stranded DNA (ssDNA) and double-stranded DNA (dsDNA). Participates in S phase and G2 phase checkpoint activation upon DNA damage.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Non-conjugated

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:FANCI

Research Areas:Epigenetics and Nuclear Signaling