FAK Monoclonal Antibody

SKU: BT-MCA2921

Size:100μL

Background:Focal adhesion kinase(FAK), with 1074 -amino acid protein(about 118 kDa), is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. FAK is concentrated at the basal edge of only basal keratinocytes that are actively migrating and rapidly proliferating in repairing burn wounds, and is activated and localized to the focal adhesions of spreading keratinocytes in culture. Thus, it has been postulated that FAK may have an important in vivo role in the re-epithelialization of human wounds. FAK protein tyrosine kinase activity has also been shown to increase in cells stimulated to grow by use of mitogenic neuropeptides or neurotransmitters acting through G protein-coupled receptors.

Research_area:Others

Target_protein:FAK

applications:

Reactivity:Human

Clonality:Monoclonal

Clone ID:4A9D6

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:FAK

Immunogen:Purified recombinant fragment of FAK expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):

UniProt accession:Q05397

Synonyms:FAK, FADK, FAK1, pp125FAK, PTK2

GeneID:5747