ERCC2 Antibody - Cat. #: CSB-PA007770ESR1HU

SKU: CSB-PA007770ESR1HU

Size :50ul

Clone Number:

Aliases:TFIIH 80 kDa subunit antibody; Basic transcription factor 2 80 kDa subunit antibody; BTF2 p80 antibody; COFS 2 antibody; COFS2 antibody; CXPD antibody; DNA excision repair protein ERCC 2 antibody; DNA excision repair protein ERCC-2 antibody; DNA repair protein complementing XP D cells antibody; DNA repair protein complementing XP-D cells antibody; EM9 antibody; ERCC 2 antibody; ERCC2 antibody; ERCC2_HUMAN antibody; Excision repair 2 antibody; Excision repair cross complementing rodent repair deficiency complementation antibody; Excision repair cross complementing rodent repair deficiency; complementation group 2 antibody; MAG antibody; MGC102762 antibody; MGC126218 antibody; MGC126219 antibody; OTTHUMP00000045860 antibody; OTTHUMP00000045861 antibody; OTTHUMP00000045862 antibody; OTTHUMP00000045863 antibody; TFIIH 80 kDa subunit antibody; TFIIH basal transcription factor complex 80 kDa subunit antibody; TFIIH Basal Transcription Factor Complex Helicase Subunit antibody; TFIIH basal transcription factor complex helicase XPD subunit antibody; TFIIH basal transcription factor complex p80 subunit antibody; TFIIH p80 antibody; TTD antibody; Xeroderma pigmentosum complementary group D antibody; Xeroderma pigmentosum group D complementing protein antibody; Xeroderma pigmentosum group D-complementing protein antibody; XPD antibody; XPDC antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P18074

Immunogen:Recombinant Human TFIIH basal transcription factor complex helicase XPD subunit protein (1-300AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background:ATP-dependent 5\\\'-3\\\' DNA helicase, component of the core-TFIIH basal transcription factor. Involved in nucleotide excision repair (NER) of DNA by opening DNA around the damage, and in RNA transcription by RNA polymerase II by anchoring the CDK-activating kinase (CAK) complex, composed of CDK7, cyclin H and MAT1, to the core-TFIIH complex. Involved in the regulation of vitamin-D receptor activity. As part of the mitotic spindle-associated MMXD complex it plays a role in chromosome segregation. Might have a role in aging process and could play a causative role in the generation of skin cancers.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:ERCC2

Research Areas:Epigenetics and Nuclear Signaling