ER alpha Polyclonal Antibody

SKU: E-AB-15624

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: ESR1

Target Synonym: DKFZp686N23123;ER alpha;ER;ER-alpha;Era;ESR;ESR1;ESR1;ESRA;Estradiol receptor;Estrogen nuclear receptor alpha;Estrogen receptor 1;Estrogen receptor alpha 3*;4;5;6;7*/822 isoform;Estrogen receptor alpha;Estrogen receptor alpha delta 3*;4;5;6;7*;8*/941 isoform;Estrogen receptor alpha delta 3*;4;5;6;7*/819 2 isoform;Estrogen receptor alpha delta 4 +49 isoform;Estrogen receptor alpha delta 4*;5;6;7*/654 isoform;Estrogen receptor alpha delta 4*;5;6;7;8*/901 isoform;Estrogen receptor alpha E1 E2 1 2;Estrogen receptor alpha E1 N2 E2 1 2;Estrogen receptor;ESTRR;NR3A1;Nuclear receptor subfamily 3 group A member 1

Research Areas: Cancer;Epigenetics and Nuclear Signaling;Neuroscience;Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat

Application: IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P03372

Accession:

Background: This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters.

Concentration: 0.6 mg/mL

Immunogen: Synthetic peptide of human ESR1

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Dilution: IHC 1:100-1:300

Calculated MW:

ObservedMW: